San Francisco 49ers running back Elijah Mitchell is expected to miss about a week due to a hamstring strain, as reported by beat reporter David Lombardi. This injury comes after Mitchell has already missed several practices. In response to this setback, the 49ers have signed veteran running back Matt Breida, who has struggled this season with the Giants, averaging only 2.7 yards per carry on 55 attempts.

San Francisco 49ers running back Christian McCaffrey is set to miss the entire preseason due to a strained calf. Coach Kyle Shanahan indicated that McCaffrey is likely to be sidelined for a couple of weeks but should be ready for the season opener against the New York Jets. The injury comes as the 49ers also deal with injuries to other running backs, including Elijah Mitchell and rookie Isaac Guerendo. In response, the team has signed former 49ers running back Matt Breida to bolster their depth at the position.

Saquon Barkley is listed as active for the game against Buffalo after recovering from an ankle injury. Although he may not have a full workload right away, Barkley will be available for Week 6.

The New York Giants are optimistic that running back Saquon Barkley will play against the Buffalo Bills despite his ankle injury. While there is no guarantee, reports suggest that there is a good chance Barkley will be on the field. Fantasy owners should keep him in their lineups but have a backup plan in case he experiences any setbacks.

Saquon Barkley's status for Week 6 against the Bills is yet to be determined due to his lingering ankle injury. Coach Brian Daboll mentioned that Barkley is closer to a return compared to tackle Andrew Thomas. In Barkley's absence, Matt Breida has struggled to lead the Giants' backfield.

Giants RB Saquon Barkley is inactive for today’s game against the Dolphins. RB Matt Breida is expected to lead the backfield, but he is only a RB3 or flex play in a struggling New York offense.

Saquon Barkley, running back for the New York Giants, is not expected to play against the Miami Dolphins due to an ankle injury. Barkley has been limited in practice all week and expressed doubt about his status. He is said to be 'closer' to a return and may be back for Week 6. In his absence, the Giants will rely on Matt Breida and Gary Brightwell in the backfield.

New York Giants star running back Saquon Barkley is unlikely to play Sunday against the Miami Dolphins due to an ankle injury. Matt Breida is expected to remain in the lead running back role for the Giants.

Saquon Barkley's status for Sunday's game against Miami is in question as he continues to recover from a high right-ankle sprain. Coach Brian Daboll stated that Barkley's availability for Week 5 may come down to a game-time decision. If Barkley is unable to play, Matt Breida will lead the Giants' backfield with Gary Brightwell available as well.

Saquon Barkley of the New York Giants continues to be limited in practice due to an ankle injury. Head coach Brian Daboll mentioned that Barkley is making progress in his recovery, but his participation in Friday's practice will determine if he can play in the upcoming game against Miami. If Barkley is unable to play, Matt Breida will likely be the team's lead back.

The New York Giants lost rookie center John Michael Schmitz and tight end Daniel Bellinger to injuries during a failed 'tush push' play in the first quarter of their game against the Seattle Seahawks. Schmitz suffered a shoulder injury while Bellinger hurt his knee. Both players are undergoing further tests to determine the severity of their injuries.

The New York Giants had a tough Week 4 loss against the Seattle Seahawks, with RB Matt Breida and TE Darren Waller posting underwhelming numbers. The Giants have been struggling in primetime games this season, being outscored 94-15. RB Saquon Barkley's potential return in Week 5 against the Dolphins could provide a spark for the team.

Saquon Barkley, the running back for the New York Giants, will not be playing in tonight's game against the Seattle Seahawks due to an ankle injury. Barkley had limited practices this week and there is a possibility of his return in Week 5. In his absence, Matt Breida is expected to be the lead back for the Giants, with Gary Brightwell and Eric Gray also active.

Saquon Barkley is doubtful for the Giants' Week 4 game against the Seahawks, which means Matt Breida will likely be the team's top running back. Breida has limited upside but could be an option for fantasy lineups in need.

The New York Giants will be without left tackle Andrew Thomas and running back Saquon Barkley is expected to be a game-time decision. Thomas is dealing with a hamstring injury and will miss his third straight game, while Barkley has a high ankle sprain and has been limited in practice. Matt Breida is expected to be the lead back in Barkley's absence, and Josh Ezeudu will fill in for Thomas.

Matt Breida had limited opportunities in the Giants' loss to the 49ers. He rushed four times for 17 yards and a touchdown, and caught all three of his targets for one yard. With Saquon Barkley injured, Breida may have a chance to be the primary early-down back in Week 4.

Giants RB Matt Breida had a tough game against the 49ers, but managed to salvage a usable fantasy performance with an eight-yard touchdown. He split carries with RB Gary Brightwell and led in snaps. Breida remains the best fantasy option in the backfield as long as RB Saquon Barkley is out.

Matt Breida is expected to start in Week 3 for the New York Giants as Saquon Barkley has been ruled out with an ankle injury.

Saquon Barkley of the New York Giants will not be playing in Thursday's game against San Francisco due to an ankle injury. Barkley sprained his right ankle in the previous game and has been listed as a non-participant in practice. The Giants have decided to hold him out, likely because of the short turnaround between games. Barkley will have more than two weeks to recover before the next game on October 2nd. In the meantime, Matt Breida is expected to lead the Giants backfield.

The New York Giants have officially ruled out running back Saquon Barkley for Thursday night's game against the San Francisco 49ers. Matt Breida is expected to be the primary running back, with Gary Brightwell and rookie Eric Gray also getting opportunities in the backfield.

ESPN's Jordan Ranaan provides insight into the Giants' backfield situation with Saquon Barkley sidelined. Ranaan expects Matt Breida to have the biggest role, citing his familiarity with the offense and reliability in pass protection. Gary Brightwell will also see some carries, while Eric Gray will be used sporadically as a runner and pass-catcher.

Giants RB Saquon Barkley is expected to miss three weeks with an ankle injury. It's an "ordinary" sprain, rather than a high-ankle sprain. Barkley's absence leaves the Giants' backfield to Matt Breida, Gary Brightwell, and rookie Eric Gray.