Ty Johnson, running back for the Buffalo Bills, is inactive for tonight's game against the Chargers due to a shoulder injury. Leonard Fournette, who recently joined the Bills, will be making his debut in this game. Fournette and Latavius Murray are options for the Saturday DFS slate, while James Cook remains a strong fantasy play.

Leonard Fournette will make his 2023 debut for the Bills against the Chargers. However, it is unlikely that he will become a fantasy asset down the stretch.

James Cook had a season-high 22 touches in the Bills' recent game against the Eagles, but his role has not necessarily grown. Despite the high number of touches, Cook's carry and opportunity shares have not increased in the past two weeks. However, Buffalo's running backs have seen an increase in target share, which could benefit Cook's fantasy numbers. Cook should be a solid PPR contributor going forward, but his touch counts may not be consistently high due to the involvement of other running backs like Latavius Murray and Ty Johnson.

Buffalo Bills running backs James Cook and Latavius Murray had a tough outing in Week 9, with Cook gaining just 39 total yards on 10 touches and Murray contributing only 10 total yards on 3 touches. Leonard Fournette was not promoted to the active roster. However, the Bills' remaining schedule is favorable for running backs, ranking 12th-easiest in adjusted fantasy points allowed.

The Buffalo Bills have signed veteran running back Leonard Fournette to their practice squad. Fournette passed a physical and will join a Bills depth chart that includes starter James Cook, as well as veterans Latavius Murray and Ty Johnson. Fournette was released by the Tampa Bay Buccaneers before the start of the 2023 league year. He had 668 rushing yards and three touchdowns, along with 523 receiving yards and three touchdown catches in 16 games last season.

RB Leonard Fournette is planning to sign with the Bills, pending a physical. The move would add Fournette to a backfield currently led by James Cook. Adding Fournette would indicate that the Bills hope he can be an upgrade over Latavius Murray and Damien Harris.

James Cook had a strong performance in Week 7, rushing for 56 yards on 13 carries and catching all 3 of his targets for 46 yards and a receiving touchdown. Latavius Murray had a quiet game with only 28 total yards on 6 touches. Cook is expected to continue being a solid RB2 option for fantasy lineups.

The Buffalo Bills have placed running back Damien Harris on injured reserve due to a neck and concussion injury. Harris is expected to miss at least the next four games, making him droppable in most fantasy leagues. With Harris sidelined, Latavius Murray is likely to see an increase in workload. Additionally, James Cook could benefit from Harris' absence in terms of volume.

Damien Harris, the running back for the Buffalo Bills, will not be playing in Sunday's game against the New England Patriots due to a neck and concussion injury. In the five games he has played this season, Harris has averaged 4.4 carries. With Harris out, Latavius Murray is expected to take on most of the workload and is worth considering as an RB3 option.

Bills running back Damien Harris suffered a neck sprain during Sunday night's game against the Giants. While the injury is not considered serious, Harris is expected to miss some time. This will likely result in an increased workload for backup running back Latavius Murray.

In Week 6's win against the Giants, Bills RB James Cook had 14 carries for 71 yards but didn't register a single target or catch. RB Latavius Murray stepped up in relief and had 12 carries for 45 yards, receiving 4 red zone carries. Murray could be a viable flex option with touchdown upside for fantasy managers.

The New York Giants are optimistic that running back Saquon Barkley will play against the Buffalo Bills despite his ankle injury. While there is no guarantee, reports suggest that there is a good chance Barkley will be on the field. Fantasy owners should keep him in their lineups but have a backup plan in case he experiences any setbacks.

The Buffalo Bills made a statement in their Week 4 AFC East matchup against the Miami Dolphins as quarterback Josh Allen connected with wide receiver Gabe Davis for an 18-yard touchdown pass on the opening drive of the game. Davis has now scored a touchdown in three straight games, which is tied for the longest streak of his career. The Bills had a balanced offensive approach, with Allen completing all four of his first four passes and the running game being utilized early with rushes from James Cook and Latavius Murray.