Chiefs RB Isiah Pacheco is active for today’s game against the Bengals, while RB Clyde Edwards-Helaire is surprisingly inactive. Pacheco is expected to have a big workload in the game.

Head Coach Andy Reid confirmed that RB Clyde Edwards-Helaire will be the starter for the Kansas City Chiefs in Week 14 against the Buffalo Bills. While it's unclear how the workload will be split among the Chiefs' running backs, Edwards-Helaire is expected to receive a significant portion of the work. Jerick McKinnon is also in the mix, along with practice-squad RBs La'Mical Perine, Deneric Prince, and Keaontay Ingram.

Emari Demercado is active for today's game after missing several weeks due to a toe injury. Michael Carter will make his debut for the Cardinals, while Keaontay Ingram will be a healthy scratch. James Conner is expected to remain the lead back for the team.

Cardinals RB Michael Carter is a healthy scratch for today's game against the Texans. With RB Emari Demercado out with an injury, Tony Jones and Keaontay Ingram will be behind James Conner.

James Conner is trending in the right direction to play in Sunday's game against Atlanta. The Cardinals designated Conner for an IR return and listed him as a limited participant in practice. Rookie RB Emari Demercado is in danger of missing another game. The Cardinals waived RB Tony Jones, indicating they expect Conner to play.

The Cardinals have elevated RB Corey Clement from the practice squad. He joins Keaontay Ingram and Tony Jones in Arizona's backfield for Sunday's game against the Browns. Fantasy managers should avoid starting any of these players.

Emari Demercado, the running back for the Arizona Cardinals, has been ruled out for Sunday's game against the Cleveland Browns due to a toe injury. With Damien Williams also on injured reserve, the Cardinals will rely on Keaontay Ingram and Tony Jones in the backfield. However, given the Browns' strong defense against running backs, it is advised to avoid starting any Cardinals running back in fantasy lineups.

Emari Demercado, running back for the Arizona Cardinals, missed his second straight practice due to a toe injury. There is concern that he may not be able to play in the upcoming game against the Cleveland Browns. With Damien Williams on injured reserve, Keaontay Ingram and Tony Jones are the remaining healthy running backs for the Cardinals.

Emari Demercado, running back for the Arizona Cardinals, did not participate in Wednesday's practice due to a toe injury. Demercado has been filling in for James Conner, who is on injured reserve, and has recorded 171 yards from scrimmage over the last three games. However, in the previous game against the Ravens, Demercado shared reps with Keaontay Ingram, who played all 29 offensive snaps in the second half. With Conner still out and Damien Williams on the practice squad injured list, Demercado's status for Sunday's game against the Cleveland Browns is uncertain. If he is unable to play, Ingram is expected to have an expanded role, while Corey Clement, Tony Jones, and Hassan Hall could be elevated from the practice squad.

The Cardinals have elevated RB Damien Williams from the practice squad, adding him to the backfield committee for Sunday's game against the Rams.

Keaontay Ingram has been cleared to play and doesn't have an injury designation for Sunday's game against the Rams. His impending return creates questions about the backfield pecking order for the Arizona Cardinals.

Keaontay Ingram, the running back for the Arizona Cardinals, has been cleared to play in Week 6 after recovering from a neck injury. With James Conner out, the backfield will also feature Emari Demercado and newly signed Tony Jones. It remains uncertain how the touches will be split among the running backs.

Keaontay Ingram, running back for the Arizona Cardinals, was limited in Wednesday's practice due to a neck injury. Ingram has been out since Week 3 but has a chance to return for Sunday's game against the Rams. The Cardinals could use Ingram as James Conner is currently on injured reserve.

Demercado is listed behind Keaontay Ingram (neck) on Arizona's Week 6 depth chart. Demercado was among the most popular waiver adds of the week after he played every single snap in the second half of Sunday's loss to Cincinnati and finished the game with 11 touches for 57 yards and a touchdown. James Conner (knee) going on injured reserve Tuesday opens up Arizona's backfield for the next four weeks, but assumptions of Demercado handling a heavy workload could be complicated by Ingram's expected return from a two-week absence due to a neck injury. Ingram opened the season as the team's No. 2 back, with he and Demercado then sharing the backup role Weeks 2-3 after Ingram finished with minus-four rushing yards in the season opener. Coach Jonathan Gannon danced around relevant questions Wednesday, telling reporters that whoever plays will get touches.

Arizona Cardinals running back James Conner has been placed on injured reserve due to a knee injury. He will miss at least the next four games and his return is uncertain. Conner is currently ranked 18th among running backs in PPR points and should be stashed in most fantasy leagues. With Conner out, the Cardinals will rely on running backs Emari Demercado, Keaontay Ingram, and Tony Jones.

James Conner of the Arizona Cardinals has been placed on injured reserve due to a knee injury. He will miss at least four games. The Cardinals will rely on undrafted rookie Emari Demercado, Keaontay Ingram, Tony Jones, and practice-squad member Corey Clement in the ground game.

Cardinals running back James Conner is expected to miss multiple weeks with a knee injury. He may be placed on injured reserve. Conner leads the team in rushing yards this season.

James Conner, running back for the Arizona Cardinals, is expected to miss multiple weeks due to a knee injury and is a candidate to be placed on IR. If placed on IR, he will have to miss at least the next four games of the season. The Cardinals will be thin at running back with Conner's absence, but they have claimed Tony Jones off waivers to provide depth. If Conner and Keaontay Ingram are unable to play in Week 6, Emari Demercado and Jones may lead the backfield.

Arizona Cardinals running back James Conner is expected to miss multiple weeks with a knee injury he suffered in Week 5. It is uncertain if Conner will be placed on injured reserve, which would cost him four games. In his absence, Emari Demercado, Keaontay Ingram, and newly acquired Tony Jones will handle the Cardinals' backfield. Ingram, who has been dealing with a neck injury, has a chance to return for Week 6, but Demercado is the best fantasy option for now.

The Cardinals have claimed RB Tony Jones Jr. off waivers from the Saints. This move suggests that RB James Conner's chances of playing in Week 6 are not looking good. RB Keaontay Ingram's availability for Sunday's game against the Rams is also uncertain. Emari Demercado is the best bet to lead Arizona's backfield for that game and is worth considering on waivers.

Arizona Cardinals running back James Conner suffered a knee injury in the second quarter of Sunday's game against the Cincinnati Bengals. He is officially questionable to return. With Keaontay Ingram also inactive due to a neck injury, the Cardinals are left with Emari Demercado as their running back.

This article provides updates on the inactives for Week 4 of the NFL season and their impact on fantasy football. Some notable players who are inactive include Derek Carr, Austin Ekeler, Odell Beckham Jr., and Deshaun Watson.