Colts wide receiver Alec Pierce will miss the upcoming game against the Tennessee Titans due to a concussion he sustained during last week's loss to the Denver Broncos. Pierce, who leads the team in receiving yards and touchdowns, leaves a significant gap in the Colts' receiving corps. His absence will allow rookie Adonai Mitchell to take on a larger role, while backup Ashton Dulin may also contribute if he returns from an ankle injury. Additionally, linebacker E.J. Speed will miss the game due to a knee injury.

The Indianapolis Colts are facing injury challenges in their wide receiver corps as Alec Pierce, Josh Downs, and Ashton Dulin missed practice due to various injuries. This situation leaves Michael Pittman, Adonai Mitchell, and Anthony Gould as the only healthy receivers heading into their upcoming game against the New England Patriots.

Indianapolis Colts wide receiver Josh Downs did not participate in Thursday's practice due to a toe injury, putting his availability for the upcoming game against the Tennessee Titans in jeopardy. If Downs is unable to play, the Colts will be without both him and Michael Pittman, leaving Alec Pierce, Adonai Mitchell, and Ashton Dulin as the primary receiving options.